By IVF is a household name; everybody might have heard about this while searching for infertility
treatments. But we will explain to you in detail what IVF is and the whole process of how IVF is
Do this so that you can acquire proper information before undergoing the treatment to achieve parenthood dreams.
Being infertile, or for any other health reasons that are stopping you from becoming a parent is
not something to blame on yourselves. Fortunately, we are in an era where we could openly talk
about infertility, and infertility treatments are no longer taboo anymore. We would like you to
remember that we are living in a world where we have cutting-edge technologies and an
experienced medical community to make ourselves up for where we are lacking.
The India Society of Assisted Reproduction says among our 27.5 million couples- about one in six
couples in urban India are dealing with infertility issues. AIIMS (All India Institute of Medical
Science) says that about 10 to 15 percent of couples in India have fertility problems. No matter
what the statistics are, even 10 percent is a significant amount that we must be concerned
about. This is why infertility treatment is of great importance. This is also why we have invested
everything best, from experienced doctors to highly advanced medical treatment methods, in
our Lifeline Fertility Center to help people sustain their generation.
These statistical numbers also imply that you are not alone and that accepting your
shortcomings and willingness to diagnose is the wisest step you will be taking in your life. So,
let’s explain IVF.
What is IVF?
IVF, also known as In Vitro Fertilization, represents a widely accepted and innovative treatment procedure for infertility. for preventing genetic disorders (inherited diseases) to help achieve a successful pregnancy. ‘In Virto’ means ‘In Glass’. IVF takes the egg from the female body (ovaries) and sperm from the
male body and combines them in a glass (Laboratory). Human fertilization takes place externally
body. Once the fertilized egg (zygote) turns into an embryo after several days, it is implanted
into the uterus to attain a successful pregnancy. This is IVF in a nutshell. IVF is a complex form of
assisted reproductive technology (ART).
Reasons for Recommending IVF
IVF doesn’t need to be the primary choice for addressing fertility problems. In our center, we
have screening procedures before recommending IVF to parents to be.
We are listing some of the conditions where IVF is performed
Low sperm count and motility
Endometriosis
PCOD (Polycystic ovary syndrome) or other ovarian conditions
Uterine fibroids
Preventing Genetic disease or disorder for the coming generation
Damaged, blocked, or diseased Fallopian tubes
Tuberculosis with damaged tubes/uterus lining
Advanced age of the woman
High age, DOR (Diminished Ovarian Reserve)
Repeated failure of IUI (Intrauterine insemination), an artificial insemination procedure for
treating infertility
The tubal transport mechanism is disturbed
Premature Ovarian Failure
Hormonal disturbances
We also move with IVF when we are unable to find a specific cause for infertility even after our
screening procedures (IVF is a welcome method around the world for unexplained infertility).
How is IVF done?
1. Consultation before anything
We have consultations, tests, and screening stages before initiating IVF. Consultation is the first
step. Our IVF specialist doctors will discuss the entire IVF process and propose an affordable
treatment plan. IVF Specialists will analyze patient history, health conditions, and treatment
history to determine the requirement for IVF. You will be guided with the pre-IVF tests,
instructions for administering fertility medications, and measures needed for readying up and
will be given all the mental support that you need. It is always wise to be open with the doctor
when talking about your history and your conditions.
2. Pre- IVF testing and Medical Examination
Our physicians (IVF specialists) order blood tests, urine tests, and screening tests for STIs and
other infectious diseases for both male and female patients to detect abnormalities in vitals.
Semen Evaluation and Ovarian reserve tests are done to determine medication and treatment
levels.
We are listing some of the tests done during the pre-cycle treatment.
Tests For Female Patients
AMH (Anti-Mullerian Hormone)
AFC Ultrasound (Antral Follicles count)
AboRh Blood Type
CBC (complete blood count)
Cytomegalovirus (CMV) IgG/IgM
Chlamydia
Gonorrhea
TSH (Thyroid-stimulating hormone) and Free T4
Antibody Screen
PAP smear
Prolactin
Syphilis
HIV ½
Varicella IgG Antibodies
Measles IgG Antibodies
Rubella IgG Antibodies
Uterine cavity evaluation (hysteroscopy or saline-infused sonography (SIS)).
Tests For Male Patients
Semen evaluation
AboRh Blood Type
Cytomegalovirus (CMV) IgG/IgM
Chlamydia
Gonorrhea
HIV ½
HTLV-I/II Antibodies
The Hepatitis B Core antibody
Hepatitis B Surface antigen
Hepatitis C antibody
Syphilis
3. Genetic Screening Test
Genetic screening tests analyze the patient’s DNA for any presence of inherent disorders or
diseases that could transfer and put the child’s life in danger. This test is done at the beginning
of the IVF procedure, before creating embryos, so that we could make more informed treatment
decisions.
4. Retrieving the Egg from the Ovaries
After our doctor reviews all the test results, and orders for medications, the patient will be taken
to the Egg Retrieval cycle. The days of the egg retrieval cycle depend on the nature of your body
and how you react to medications. Normally it would be from 10 to 14 days. The egg retrieval
cycle is counted when the medication procedure for ovarian stimulation begins. The ovarian
cycle in a healthy female at reproductive age produces multiple eggs each month. Usually, one
egg becomes mature to ovulate, and the rest of them disintegrates. In the ovarian stimulation
stage of IVF, hormone medications are given to the patient so that the entire group of eggs gets
mature. Ovaries are monitored with ultrasounds and blood hormone levels. Follicles (little sacks
inside ovaries holding a single egg) greater than 14 mm
is considered to have a matured egg. You will be given pain medication and will be sedated
before egg retrieval. Egg retrieval is done 36 hours after the last hormone injection, usually
called – the trigger shot.
The transvaginal ultrasound aspiration method is used for egg retrieval. An ultrasound probe is
inserted into the patient’s vagina to identify the ovarian follicles. Once identified, using
ultrasound guidance, a thin needle is inserted through the patient’s vagina to retrieve eggs from
the follicles. The needle is connected to a suction device, which retrieves multiple eggs in about
20 minutes. Eggs are placed in a culture medium and incubated for the sperms for the
fertilization process. Egg retrieving may inflict cramping on patients.
5. Retrieving Sperms
We collect the partner’s sperm almost at the same time as egg retrieval. Masturbation is the normal
method of collecting a semen sample. Next, we separate the sperm from the semen fluid. For
In special cases, we use testicular aspiration methods, which involve surgical steps to extract
sperm directly from the partner’s testicle. Also, if a man can’t release or produce the required
amount of healthy sperm (azoospermia), the micro-TESE (Microscopic testicular sperm
extraction) is done. It is a procedure in which sperms are directly retrieved from seminiferous
tubules of the testis under a microscope. This method has sperm retrieval rates from 40% to
60% and helps in those patients who has a negative result for testicular biopsy.
6. Fertilization
There are two common methods for fertilization. Conventional IVF and Intracytoplasmic sperm
injection (ICSI).
In conventional IVF, we combine healthy sperm with mature eggs and incubate the mixture. Conversely, intracytoplasmic sperm injection (ICSI) directly injects healthy sperm into all the mature eggs.
eggs. Our specialists select the appropriate method based on patient condition and history.
Egg retrieval and fertilization occur on the same day. The observed average count shows a 70
percent fertilization rate from retrieved matured eggs.
7. PGT- A Testing
Preimplantation genetic testing (PGT- A Testing) determines chromosomal abnormalities and culturing fertilized embryos for 5 to 7 days helps us identify and prevent certain diseases and disorders from being passed to the child. Then they are biopsied and undergo PGT- A testing.
8. Embryo Development & Transfer
After completing fertilization, we monitor the development of the embryo for five to six days before
transferring to the uterus. From the fertilized eggs about 50 percent will reach the blastocyst
stage, which is the perfect stage to take them to the uterus. We call this transfer cycle as FET
(Frozen embryo transfer) cycle. Conduct embryo transfer between days 19 and 21 of the
menstrual cycle. Perform a blood test for pregnancy after 10 days of implantation. After 10 weeks of
after the “pregnancy follow-up,” transfer the patient to the obstetrician’s care.
9. What if a cycle fails?
The first attempt won’t always find success. But everyone finds success within a few attempts.
Normally after 3-6 months after the egg retrieval procedure (ovaries require rest for the period),
Initiate a second attempt. Our IVF doctors will always be in assistance with you. For a failed
embryo transfer, we could make a second attempt after one month.
Lifeline’s Part in Divine Making
Our IVF success rate is 80%, a higher number than the average international figure, and we are
striving to increase the figure every year. We are maintaining a 95% survival rate, with a
specialization in treating extremely preterm babies from 430 grams. Our IVF specialists exercise
high ethical conduct and professional vision, and we always acquire the latest technology to help
them achieve maximum precision in every procedure. We must be aware that the most
important factors in the success of an IVF are the ‘quality’ of the egg, sperm, and uterus. We
Facilitate the divine union of egg and sperm and ensure that it plants itself in the uterus. If you
would like to talk with our specialists or if you need an online consultation, you can easily book
an appointment through our website.
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